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Serious Skincare A-Defiance Night Cream A Intensive Retinol Night Cream

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Overview & Details

Serious Skincare A-Defiance Night Cream A Intensive Retinol Night Cream
Smooth on this intensive retinol beauty treatment before crawling into bed, and every night can be a great night. That's because this vitamin-enriched cream helps moisturize and soften your complexion while you sleep. So you can start each new day with a complexion that looks renewed and refreshed!

What You Get
  • 2 fl. oz. A Defiance Night Cream A - Intensive Retinol Night Cream 

What It Does
  • Helps moisturize and soften skin

Good to Know
  • Apply nightly to freshly-cleansed skin.
  • Can be worn over a serum or alone.
Shop all Serious Skincare



  • Overnight beauty treatment
  • Vitamin-rich formula
  • Formulated with retinol and other fine ingredients
  • Helps soften the complexion
  • Supports healthy skin cell renewal



Ingredients: Water, Octyldodecyl Myristate, Caprylic/Capric Triglyceride, Simmondsia Chinensis (Jojoba) Seed Oil, Dicaprylyl Ether, Glycerin, Polyethylene Glycol, Cetyl Alcohol, Niacinamide, Acetyl Hexapeptide-8, Glycereth-26, Glyceryl Stearate, Retinyl Palmitate, Panthenol, Tocopheryl Acetate, Tetrahexyldecyl Ascorbate, Retinol, Methacrylates Crosspolymer, Polyacrylate-13, Polyisobutene, Polysorbate 20, Chondrus Crispus (Carrageenan), Acacia Decurrens/Jojoba/Sunflower Seed Wax/ Polyglyceryl-3 Esters, PEG-75 Stearate, Ceteth-20, Steareth-20, Allantoin, Caffeine, Bisabolol, Disodium EDTA, Triethanolamine, Aloe Barbadensis Leaf Juice, Sodium Hyaluronate, Resveratrol, Fragrance, Phenoxyethanol, Ethylhexylglycerin.


Serious Skincare A-Defiance Night Cream A Intensive Retinol Night Cream

82 reviews 4.3 out of 5
5 Star
70.73% 58
4 Star
9.76% 8
3 Star
4.88% 4
2 Star
3.66% 3
1 Star
10.98% 9
Would recommend to a friend
  • Love, love, love!

    This by far is the best night cream I've ever found!

    Brae-Elle3, SD
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  • So pleased!!!

    First, I have to say, I'm totally happy with this product! This has been one of the best Retinol Night Creams I've used! This product was one of my first SS skincare items, and I was nervous about using this. I have sensitive skin, and many products break me out, due to fragrance and other bad ingredients. This made my skin so smooth and firm, after just one night. I did notice my pores appeared smaller. I did experience some dryness, after using this three nights in a row, but I just doubled up on my hydrating day time moisturizers and made sure to exfoliate and my skin was fine. I have used Retinol products in the past and it is common for me, to experience some dryness, but I find exfoliating and using a super hydrating moisturizer works. I of course use a high end Sunblock. This product is super effective right after using my GLOPRO device. I would definitely recommend this!

    MMTBeauty, CA
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  • Best skin care ever

    I am in the beauty industry and as a stylist i have to look my best always..I have only been using this product for about two weeks and i can already see the differences in my ski, better yet it was almost immediately i started to use it, i have used from the most expensive ones to less and i can actually say this one have my vote.My skin looks and feels younger and my pores are close and looking fantastic.....Thank you! Serious Skin care Lonny

    Lonny08, FL
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  • The best night cream...

    This is such an effective cream, the texture on my face becomes smooth and skin tone evens out. It is not too strong or drying. It really shows nice results very quickly. I've been using for years and I'm happy I got on the auto shipment plan. I always end up going back to Serious Skincare A-Defiance - even after trying others throughout the years. This is always in my cabinet.

    Nancyweber, CA
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  • FAB!

    I have fair Celtic skin, but am able to use this day and night as its very gentle and really softens my skin. Sometimes I use it over SSC Glycolic pads for extra boost - tingles a little with this combo but that fine as it only last a minute. Bought it on sale; then after a week bought it again when auto ship popped up:-). LOVE!!

    queenvictoria, IL
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Serious Skincare

Discover a comprehensive way to address all your skincare needs. Whether you struggle with fine lines and wrinkles, dull-looking skin or acne, Serious Skincare offers a customized regimen of products developed by a team of chemists and aestheticians. Give your complexion the care it deserves with this complete line of skincare solutions.