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4.0 out of 23 reviews READ REVIEWS

PRAI Extreme Derma-Dose Solution Duo

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Overview & Details

PRAI Extreme Derma-Dose Solution Duo 

What It Is
2-step skincare system that helps soften, rejuvenate, soothe and moisturize aging skin

What You Get

  • 1 fl. oz. Extreme Derma-Dose Serum Solution 
  • 1 fl. oz. Extreme Derma-Dose Creme Solution

What It Does
Extreme Derma-Dose Serum Solution

  • Helps exfoliate skin 
  • Helps improve the appearance of lines and wrinkles 
  • Helps optimize skin's own natural collagen levels 
  • Helps optimize skin's elasticity 
  • Helps firm the appearance of skin

Extreme Derma-Dose Creme Solution

  • Contains Dermal Rx HydroSeal, Neossance Squalane and other key ingredients
  • Helps reduce the appearance of wrinkles 
  • Helps optimize skin's own natural collagen levels 
  • Helps reduce the appearance of rough skin 
  • Helps improve skin's moisturization and emolliency

Consumer Perception Survey

In a consumer perception survey of 30 compensated women who used the Prai Extreme Dermadose Creme along with the Extreme Dermadose Serum daily for 7 days:

  • 90% said that the appearance of lines and wrinkles were improved and looked less visible
  • 90% said that skin looked and felt moisturized

How to Use

  • Every third month, replace your existing skincare regimen with this 2-step system for 1 week.
  • Step 1: Apply Extreme DermaDose Serum Solution to clean face morning and/or evening.
  • Step 2: Apply Extreme DermaDose Creme Solution both morning and/or evening.

Made in USA

Good to Know
  • Dermal Rx HydroSeal is a registered trademark of Biocogent, Inc.
  • Neossance Squalane is a trademark of Centerchem, Inc.
  • Derm SRC PF is a trademark of Barnett Products Corporation.
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PRAI Extreme Derma-Dose Creme Solution -1floz
Ingredients: Aqua/Water/Eau, Glycerin, Isohexadecane, Butylene Glycol, Cetyl Alcohol, Caprylic/ Capric Triglyceride, C12-15 Alkyl Benzoate, Cetearyl Alcohol, Squalane, Yeast Extract, Soy Amino Acids, Sodium Hyaluronate, Isodecyl Isononanoate, C4-24 Alkyl Dimethicone/Divinyldimethicone Crosspolymer, Polydiethyleneglycol Adipate/IPDI Copolymer, Zingiber Cassumunar Root Oil, Cetearyl Glucoside, Behenyl Alcohol, Tetrahydroxypropyl Ethylenediamine, Carbomer, Caprylyl Glycol, Xanthan Gum, Disodium EDTA, Phenoxyethanol, O-Cymen-5-OL, Fragrance (Parfum), Amyl Cinnamal, Benzyl Salicylate, Citronellol, Geraniol, Hexyl Cinnamal, Butylphenyl Methylpropional, Limonene, Alpha-Isomethyl Ionone.

PRAI Extreme Derma-Dose Serum Solution -1floz
Ingredients: Aqua/Water/Eau, Cyclopentasiloxane, Glycerin, Butylene Glycol, Isododecane, Isohexadecane, HDI/Trimethylol Hexyllactone Crosspolymer, Neopentyl Glycol Diheptanoate, Sodium Chloride, Lauryl PEG-9 Polymethylsiloxyethyl Dimethicone, Polybutene, Glucosamine HCI, Pisum Sativum (Pea) Extract, Bambusa Vulgaris Stem/Leaf Extract, Polysilicone-11, Cetyl PEG/PPG-10/1 Dimethicone, Zingiber Cassumunar Root Oil, Tocopheryl Acetate, Silica, Xanthan Gum, Tetrasodium EDTA, Sodium Hydroxide, Polyethylene, Dimethicone/Divinyldimethicone/Silsesquioxane Crosspolymer, Phenoxyethanol, Fragrance (Parfum), Amyl Cinnamal, Benzyl Salicylate, Geraniol, Hexyl Cinnamal, Butylphenyl Methylpropional, Limonene, Alpha-Isomethyl Ionone, Bismuth Oxychloride (CI 77163).


PRAI Extreme Derma-Dose Solution Duo
23 reviews 4.0 out of 5

Review Breakdown

5 Star
65.22% 15
4 Star
13.04% 3
3 Star
0% 0
2 Star
4.35% 1
1 Star
17.39% 4
Would recommend to a friend
  • Prai Extreme Derma-Dose Solution Duo

    I love this duo. I have tried many items for my skin but this has by far worked better than any. It noticeably made my skin younger and firmer looking.

    thia22, NC
    Was this review helpful? 4 out of 4 found this review helpful

    I love these products. I know Kathy said we were only supposed to use it for a week and then take a break, however, I was not sensitive to it so I used it every day until both bottles were empty and my skin feels so much firmer and even. I will purchase this again and again and again and incorporate them as part of my daily routine. Great duo!!

    Kimona, FL
    Was this review helpful? 10 out of 10 found this review helpful
  • 3 Times Only 4 Sensitive Skin

    Started at PM, then the next morning & evening. I only stopped because i didn't want to take the chance & have a breakout and an obvious return. My skin looked so radiant! I'm 68 & been using skincare since i was 55 when i started to see some changes. They were bad but it was time to change. So i went from Principal Secret to Prai because of frown lines, jar drooping, and wrinkled necklines. Kyani skincare didn't get rid of the altogether lines.

    Health_Girl, FL
    Was this review helpful? 7 out of 10 found this review helpful
  • Fabulous! Another Winner

    I have been using the Prai 24 K Gold Caviar serum and cream daily for over a year, along with the throat and neck serum and cream. Love them all. Wasnt sure what to expect with this, but used it last night for the first time. Wow! I couldnt help but notice a difference this morning. It was like a soft focus lense. Truly. I am 58 and take care of my skin but I saw a difference. Just put my 3rd dose on and my skin looks and feels wonderful.

    njms, MD
    Was this review helpful? 11 out of 12 found this review helpful

    First if all, I AM NOT A COMPENSATED USER!!! I used this product as recommended and noticed a difference the morning after using for the first tine. Lines from nose to corner of mouth have greatly diminished, as have the fine lines around my eyes. My skin was brighter, softer, and much smoother. I don't know why we can only use for a week every 3 months. I would use this every day. I've only been using PRAI since March of 2017 but I am a convert and will be getting rid of all my other products. Every PRAI product I've used, has delivered. Thanks Cathy.

    Rosebud056, MI
    Was this review helpful? 22 out of 22 found this review helpful


PRAI is a world-renowned skincare company dedicated to creating age-defying beauty products infused with their exclusive, signature ingredient: Prai Root essence.  Passionate about offering skincare with high-performance ingredients and innovative technology to all women, their vast array of products boasts results-oriented formulas with luxurious, silky textures.