2.8 out of 42 reviews READ REVIEWS

Beauty Bioscience R45 The Reversal Phase 4

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Product Description

Beauty Bioscience R45 The Reversal Phase 4

What It Is
The most concentrated phase from the R45 multi-phase beauty treatment.

What You Get

  • (2) .17 fl. oz. R45: The Reversal Regeneration Complex Phase 4

What It Does

  • Increasing concentrations of key ingredients to help address the look of fine wrinkles, skin tone evenness, pores, and skin spots for overall younger-looking skin
  • Wrinkle-filler alternative (helps plump wrinkles)
  • Titration Therapy mitigates the traditional side effects associated with highly active Vitamin A products
  • Proprietary mixture of Vitamin A and peptides; formulated to help address many major aspects of aging including wrinkles, skin tone evenness, pores, and skin spots; optimizes the epidural layers of the skin and assists with your natural cell turnover
  • Retinoid concentration in Phase 4 is 67% more concentrated than Phase 3; Phase 4 is the highest level of concentration within R45's Titration Therapy

How to Use

  • Use at night for 2 weeks after completing Phase 3 from R45: The Reversal (sold separately).
  • Apply on clean skin.
  • Order of application:
    - Cleanse with a gentle cleanser.
    - Use a pump of A and a pump of B on Phase 1 nightly (sold separately).
    - Once 2 weeks have elapsed, switch over to Phase 2 and repeat process until finished with Phase 3, moving on to Phase 4 if desired.
  • After a nightly R45 application it is recommended that you moisturize with a serum and/or a non-anti-aging moisturizer.
  • Use once nightly for the time frame above.
  • Recommended for use twice yearly but can be used more often if desired.

Made in USA
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Beauty Bioscience R45 The Reversal Phase 4
42 reviews 2.8 out of 5

Review Breakdown

5 Star
28.57% 12
4 Star
2.38% 1
3 Star
19.05% 8
2 Star
16.67% 7
1 Star
33.33% 14
Would recommend to a friend
  • 97084monica, OR

    Love this stuff

    This is great for the skin.. Really helps with wrinkles.. I wish the bottle was larger though.. Runs out really quck

    Was this review helpful? 1 out of 1 found this review helpful
  • NDHR, PA

    Retinol product

    I bought the whole system. Starting with phase 1 through 3. Currently on phase 2. It is working wonderfully, no skin irritation so far and my face is so soft to touch. I wish I would have started using this product years ago, I'm 63.

    Was this review helpful? 1 out of 1 found this review helpful
  • schurman, SD


    If you want your skin to glow...try Bioscience. I love everything I have bought. Worth the cost! Love you, Jamie!!

    Was this review helpful? 0 out of 0 found this review helpful
  • renee636, CA

    Can't do with out

    After my first use, I make sure I have it on hand.

    Was this review helpful? 0 out of 0 found this review helpful
  • deniselynne19888, TX

    Phase 4

    I have completed the first three bioscience and beforecfinishing with phase 4 aI am getting compliments on my skin. Of course I am using the glo pro with this product. The glo pro has made a massive effect on getting products and serums deeper into my skin. Thanku bioscience

    Was this review helpful? 10 out of 10 found this review helpful

About The Brand


After spending years helping to develop cutting-edge beauty technology and products for prominent cosmetics companies, Jamie O'Banion and Dr. Terry James created new patented technology so exceptional they decided to launch it themselves. Beauty Bioscience is all fact and no fluff, delivering real results with carefully edited products that actually work, from the award-winning GloPRO® tool to cult-following topicals. BeautyBio babes around the world celebrate a new era of empowered confidence inside and out. The results truly speak for themselves!